Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if Dexmedetomidine given at the end of surgery will reduce postoperative morphine consumption and improve postoperative quality of recovery as compared to morphine in patients undergoing laparoscopic bariatric surgery.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: American University of Beirut Medical Center
• Treatments: Dexmedetomidine; Morphine

Criteria

Inclusion Criteria:

• Body Mass Index > 40 kg/m2 or BMI > 35 kg/m2 with comorbid conditions such as hypertension, diabetes or sleep apnea

• American Society of Anesthesiologists class I or II

• Undergoing laparoscopic sleeve gastrectomy bariatric surgery

Exclusion Criteria:

• Allergy to morphine or its derivatives

• Allergy to α-2 adrenergic agonists

• weight over 180 kg

• history of uncontrolled hypertension

• heart block greater than first degree

• prolonged QT interval

• clinically significant neurologic, cardiovascular, renal, hepatic, or gastrointestinal diseases

• received an opioid analgesic medication within a 24 h period prior to surgery

• history of alcohol, drug abuse or chronic opioid intake

• history of psychiatric disorder

• pregnant or breastfeeding.