Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Block.
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
The duration of sensory block after single dose of long acting local anesthetics is not
sufficient to avoid the postoperative use of opioids. Alpha-2 adrenoceptor agonists such as
clonidine have been shown to increase the duration of peripheral nerve block. Dexmedetomidine
is a more potent and selective α-2-adrenoceptor compared to clonidine. To the best of our
knowledge, the use of Dexmedetomidine in different dose levels as adjuvant to local
anesthetic was not previously reported for femoral nerve block.