Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Postoperative agitation (hyperactive delirium) is common following major surgery(incidence
was about 20% in our pilot study). Dexmedetomidine was related to a reduced delirium rate
when comparing with midazolam in many clinical settings. It is not clear if dexmedetomidine
is useful on reducing postoperative delirium. The hypothesis of present study: intraoperative
application of dexmedetomidine (0.2ug/kg/h) is is effective (50% reduce) than placebo for
reducing of early postoperative delirium and increase postoperative quality of recovery
within 24 postoperative hours.