Dexmedetomidine vs Midazolam for Intraoperative Sedation
Status:
Completed
Trial end date:
2017-05-01
Target enrollment:
Participant gender:
Summary
This randomized, open clinical trial sought to compare the use of Midazolam and
Dexmedetomidine during surgery in patients under regional anesthesia.
The primary objective was to determine the superiority of either drug during the
intraoperative period regarding: 1- Depth of sedation and 2- incidence of complications.
Secondary objectives included the determination of superiority regarding the postoperative
period.
For that, patients were randomized into two groups and sedated with either Midazolam or
Dexmedetomidine.
Phase:
Phase 4
Details
Lead Sponsor:
Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo