Oral mucositis can be a significant problem for cancer patients. It is typically associated
with pain and increased risk of infection and can lead to impaired nutritional status and
inadequate hydration.it can be seen in the patient population receiving high-dose head and
neck radiation therapy (85%-100%). Topical dexpanthenol acts like a moisturizer, improving
stratum corneum hydration, reducing transepidermal water loss and maintaining skin softness
and elasticity. The stimulation of epithelization, granulation and mitigation of itching were
the most prominent effects of formulations containing dexpanthenol. The investigators suppose
that dexpanthenol mouth wash may improve oral mucositis.