Dextromethorphan Added on for Children With Chronic Irritability

• Status: Not yet recruiting
• Trial end date: 2022-07-31
• Target enrollment: 0
• Participant gender: All

Summary

Dextromethorphan Added on for Children With Chronic Irritability

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tri-Service General Hospital
• Treatments: Dextromethorphan

Criteria

Inclusion Criteria:

• Patients aged 7 to 17 who have irritability symptoms will be recruited. They will be screened for the irritability symptoms with ARI scale.

Exclusion Criteria:

• Patients who are not willing to participate in the study after detailed explanation.

• Patients who could not follow the investigator's instructions.

• Patients who have problems to express questions or emotional problems exactly.

• Patients who have severe neurological or mental illness like epileptic disorder, history of stroke, schizophrenia, bipolar disorder, mental retardation or uncontrolled suicide risk.

• Patients who have severe medical illness or surgical conditions like uncontrolled abnormal thyroid function, history of heart attack, uncontrolled hypertension.

• Patients who are allergic to methylphenidate or dextromethorphan.

• Patients with autoimmune disorders

• Patients with asthma or severe infection disorder currently or in the previous two months to avoid the influence of the level of cytokines.