Overview

Diabetic Macular Edema Asian Response (DEAR) Study: Biomarkers for Response to Aflibercept in Asian Patients With Center Involving DME

Status:
Unknown status

Trial end date:
2021-03-01

Target enrollment:

Participant gender:

Summary

To investigate whether ocular imaging and proteomic biomarkers; and systemic biochemical, metabolomic, and genetic biomarkers predict treatment response to intravitreal aflibercept in a cohort of patients with DME.

Phase:

Phase 4

Details

Lead Sponsor:

Singapore National Eye Centre

Collaborators:

Santen Pharmaceutical Co., Ltd.
Singapore Eye Research Institute

Treatments:

Aflibercept
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate