Overview

Diagnosis of Metastatic Tumors on 68Ga-FAPI PET-CT and Radioligand Therapy With 177Lu-EB-FAPI

Status:
Recruiting
Trial end date:
2023-04-01
Target enrollment:
0
Participant gender:
All
Summary
FAP is a fibroblast activation protein and overexpressed in many tumor tissues. This study is intended to conduct preliminary clinical transformation and internal irradiation dosimetry research on 177Lu-EB-FAPI--a new 177Lu therapeutic drug modified by Evans Blue (EB) for the first time in the world.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Peking Union Medical College Hospital
Criteria
Inclusion Criteria:

- confirmed treated or untreated metastatic tumors patients;

- 68Ga-FAPI PET/CT and 18F-FDG PET/CT within two weeks;

- signed written consent.

Exclusion Criteria:

- pregnancy;

- breastfeeding;

- any medical condition that in the opinion of the investigator may significantly
interfere with study compliance