Diagnostic Accuracy of Ferumoxytol-Enhanced MRI for Detecting Lymph Node Metastases in Colorectal Cancer

• Status: Withdrawn
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the diagnostic accuracy of ferumoxytol-enhanced MRI in detecting lymph nodes that have been invaded by tumor cells in patients with colorectal cancer.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Scott Potenta, MD, PhD
• Treatments: Ferrosoferric Oxide

Criteria

Inclusion Criteria:

• Patients 18 years of age or older with histologically confirmed colorectal cancer

• Planned for surgical resection of tumor

Exclusion Criteria:

• Contraindications for MRI

• Contraindication or known allergy to ferumoxytol or parental iron products (e.g. iron sucrose, iron dextran, etc.)

• Planned chemotherapy or radiation treatment prior to surgical resection of primary tumor

• Uncontrolled serious medical illness

• Unable or unwilling to give informed consent

• Pregnancy

• Breastfeeding women

• Clinically documented or known risk of primary or secondary iron overloading including history of thalassemia, sickle cell anemia, hereditary hemochromatosis or first-degree relative with known hemochromatosis, multiple transfusions for any reason within the past 5 years, or use of over-the-counter ferrous sulfate without the supervision of his/her doctor