Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine

• Status: Not yet recruiting
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to investigate the effect of different crystalloid coload volumes on the 90% effective dose of prophylactic norepinephrine infusions for preventing postspinal anesthesia hypotension during cesarean section.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: General Hospital of Ningxia Medical University

Criteria

Inclusion Criteria:

• 18-45 years

• Primipara or multipara

• Singleton pregnancy ≥37 weeks

• American Society of Anesthesiologists physical status classification I to II

• Scheduled for cesarean section under spinal anesthesia

Exclusion Criteria:

• Body height < 150 cm

• Body weight > 100 kg or body mass index (BMI) ≥ 40 kg/m2

• Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg

• Hemoglobin < 7g/dl

• Fetal distress, or known fetal developmental anomaly