Different Doses of IVIG for Kawasaki Disease

• Status: Completed
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to investigate the effect of different doses of intravenous immunoglobulin (IVIG) (1g/kg once, 1g/kg twice, 2g/kg once) for Kawasaki disease (KD) in a multicentre, prospective,randomised trial.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Hospital of Fudan University
• Collaborators: Children's Hospital of Shanghai Jiaotong University; Shanghai Children's Hospital; Shanghai Children's Medical Center
• Treatments: gamma-Globulins; Immunoglobulins, Intravenous; Rho(D) Immune Globulin

Criteria

Inclusion Criteria:

• Individual patient's medical file data confirmed the diagnosis of KD using the 5th revised edition of diagnostic criteria for KD, issued by the Japan Kawasaki Disease Research Committee at the 7th International Kawasaki Disease Symposium in 2002.

• the patients aged from 1 months to 12 years old.

• All included patients required to sign an informed consent form.

• the patients didn't receive treatment before.

Exclusion Criteria:

• The patients with the application of hormone or other immunosuppressive agents;

• The patients didn't want to signed informed consent.