Different Doses of Nebulized Magnesium Sulphate in Status Asthmaticus

• Status: Not yet recruiting
• Trial end date: 2022-12-30
• Target enrollment: 0
• Participant gender: All

Summary

In this study investigators will use magnesium sulphate in the nebulized form in children between 2 and 12 years of age as an acute reliever for acute severe asthma. Aim of this study is to determine that whether adding low (250mg), intermediate (500mg), and high doses (750mg) of magnesium sulphate in the 1st hour of treatment has any difference in the improvement of clinical condition of the patient and length of hospital stay. There will be total 108 patients having 2 groups. 1st group will receive only Ventolin while 2nd group will be given Ventolin and Magnesium sulphate.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ziauddin University
• Treatments: Albuterol; Magnesium Sulfate

Criteria

Inclusion Criteria:

1. Children between 2 to 12 years of age.

2. Children with the diagnosis of asthma having a pram score of more than 4.

3. Children with reactive airways

Exclusion Criteria:

1. Critically ill children who require intubation or mechanical ventilation.

2. Having hypersensitivity or allergy to MgSO4.

3. with history of chronic lung impairment.

4. Whose parents are not giving informed consent for participation in research.