Overview

Different Doses of Vitamin A and Childhood Morbidity and Mortality

Status:
Completed
Trial end date:
2003-08-01
Target enrollment:
0
Participant gender:
All
Summary
Vitamin A supplementation reduces all-cause mortality. It is therefore given with oral polio vaccine in national campaigns. However, it is not clear which dose is optimal. The two studies that have investigated the impact of different doses of vitamin A have both found that a smaller dose was better than a large dose. We therefore investigated if a smaller dose given with oral polio vaccine gives equal or better effect.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Bandim Health Project
Treatments:
Retinol palmitate
Vitamin A
Vitamins
Criteria
Inclusion Criteria:Between 6 mo and 5 years old and thus eligible for OPV and vitamin A
during national immunisation day

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Exclusion Criteria:Children with overt signs of vitamin A deficiency will not be enrolled
in the study, but treated according to the recommendations. -