Different Noradrenaline Protocols in Post Spinal Hypotension in CS

• Status: Not yet recruiting
• Trial end date: 2021-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

The incidence of hypotension after spinal anesthesia is approximately 60% in parturients undergoing cesarean section. As a consequence of hypotension, nausea-vomiting, dyspnea and neurological deterioration in patients and low Apgar scores in newborns may occur. Therefore, there is an increasing interest to prevent maternal post spinal hypotension by using several drugs including noradrenaline given in different protocols to the patients undergoing spinal anesthesia for cesarean section. However, there is no conclusive answer to the question of which dosage is the best to prevent the maternal post spinal hypotension in literature.

In this prospective randomized study, we aimed to compare different noradrenaline protocols for preventing maternal post spinal hypotension during elective cesarean delivery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ankara University
• Treatments: Norepinephrine

Criteria

Inclusion Criteria:

• ASA 2

• 38 +4 gestational age parturient

Exclusion Criteria:

• ASA 3-6

• Parturients with any kind of contraindication to spinal anesthesia

• Hypertensive parturients (basal systolic blood pressure above 140 mmHg)

• Parturients having basal systolic blood pressure below 100 mmHg

• Parturients having peripartum hemorrhage

• Parturients having body mass index above 40

• Parturients with a known allergic reaction to one of the study drugs

• Parturients not willing to be included into the study