Dilute Bleach Compresses for Radiation Dermatitis

• Status: Recruiting
• Trial end date: 2023-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is looking at the safety of applying dilute bleach compresses to patients receiving radiation therapy and the impact of these dilute bleach compresses on the frequency and severity of skin changes that occur during radiation therapy.

The names of the study interventions involved in this study are:

• Di-Dak-Sol: dilute bleach compresses

• White petrolatum ointment

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dana-Farber Cancer Institute
• Treatments: Eusol; Petrolatum; Sodium Hypochlorite

Criteria

Inclusion Criteria:

• Diagnosed with a rhabdomyosarcoma or other sarcoma requiring RT

• 12 to 25 years of age

• Scheduled for a RT planning session (CT simulation)

• Have a scheduled RT start date within 1 to 2 weeks from the CT simulation

• Will be receiving doses of radiotherapy greater than at least 36 Gy

• Subjects may participate in other studies, including therapeutic trials.

• Ability to comply with at-home dilute Di-Dak-Sol compresses for final week of dilute Di-Dak-Sol compresses following radiation treatment.

• Ability to understand and/or the willingness of their parent or legally authorized representative to sign a written informed consent document.

Exclusion Criteria:

• Patients who are pregnant, which may result in discontinuation of RT

• Presence of inflammatory skin lesions in the radiation field that could interfere with assessment