This is a prospective, double-arm study designed to evaluate the tolerability of direct
peritoneal resuscitation (DPR) in neonates with gastroschisis. The experimental arm (DPR
group) will receive adjuvant DPR with standard treatment for gastroschisis (staged silo
closure). The control arm (SoC group) will receive standard treatment for gastroschisis
without DPR.
The Research Team will prospectively enroll all neonates with the diagnosis of gastroschisis
presenting to ACH within 12 hours after birth for whom consent is signed by the
parent(s)/legally authorized representative (LAR). The Research Team anticipates enrolling 40
subjects at Arkansas Children's Hospital. All subjects that have their abdominal wall defect
closed will be defined as having completed active participation in the study.