Overview

Discovery Stage IND EXEMPT SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms

Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Explore the relationship between drug target topoisomerase II gene single nucleotide polymorphisms and Etoposide (VP-16) therapeutic-effects in patients with small cell lung cancer, based on Oxford precisely sequencing drug targets' genes. Explore the relationship between drug target CYP4503A4 gene single nucleotide polymorphisms and Etoposide (VP-16) side-effects in patients with small cell lung cancer, based on Oxford precisely sequencing drug targets' genes.
Phase:
Phase 3
Details
Lead Sponsor:
Dr. Han Xu, President/CEO / PD / PI / Monitor / IRB Chair
Han Xu, M.D., Ph.D., Sponsor-Investigator, IRB Chair
Collaborator:
PPD
Treatments:
Cisplatin
Etoposide
Etoposide phosphate