Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks
Status:
Suspended
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
The primary objectives of this study are to define the extent of dermatomal anesthesia and
anatomical spread of injectate (as defined by MRI imaging) that is provided by an ESP block
at the T5 level, using twenty milliliters of 0.5% ropivacaine.
The secondary objectives include: 1) the measurement of changes in hemodynamic parameters
associated with the ESP block, 2) the duration of sensory effects provided by ropivacaine
with or without epinephrine, 3) the venous plasma concentration of ropivacaine associated at
various time intervals after completion of the ESP block.