Disulfiram Plus Arsenic Trioxide In Patients With Metastatic Melanoma and at Least One Prior Systemic Therapy
Status:
Terminated
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
This phase I trial is studying the side effects and best dose of arsenic trioxide when given
together with disulfiram in treating patients with metastatic and progressive melanoma. Drugs
used in chemotherapy, such as disulfiram and arsenic trioxide, work in different ways to stop
the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Giving more than one drug (combination chemotherapy) may kill more tumor cells.