Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse

• Status: Completed
• Trial end date: 2007-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Sixty patients were randomized to receive either placebo or diazepam in addition to mechanical physiotherapy and analgesics for the first 7 days of conservative treatment of clinically and radiologically confirmed lumbar disk prolapse

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Tuebingen

Criteria

Inclusion Criteria:

• sciatica without or with neurological deficit attributable to lumbar disc prolapse

• CT or MRI confirmation of lumbar disc prolapse

• informed consent

Exclusion Criteria:

• bladder or bowel disturbance

• acute (< 24 h) development of paresis grade 1 or plegia

• taken benzodiazepines for more than 2 weeks

• history of benzodiazepine intolerance

• prior surgery for disc prolapse, or prior trauma to the vertrebral column