Docetaxel, Prednisone, and Vatalanib in Treating Patients With Advanced Prostate Cancer
Status:
Terminated
Trial end date:
2006-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as docetaxel and prednisone, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Vatalanib may stop the growth of tumor cells by blocking some of the enzymes needed
for cell growth and by blocking blood flow to the tumor. Giving vatalanib together with
docetaxel and prednisone may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of vatalanib when
given together with docetaxel and prednisone and to see how well they work in treating
patients with advanced prostate cancer.