Docetaxel With or Without PI-88 in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing. PI-88
may stop the growth of non-small cell lung cancer by blocking blood flow to the tumor. It may
also help docetaxel work better by making tumor cells more sensitive to the drug. Giving
docetaxel together with PI-88 may kill more tumor cells. It is not yet known whether giving
docetaxel together with PI-88 is more effective than docetaxel alone in treating non-small
cell lung cancer.
PURPOSE: This randomized phase II trial is studying docetaxel and PI-88 to see how well they
work when given together compared to docetaxel alone in treating patients with stage IIIB or
stage IV non-small cell lung cancer.