Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in Bladder
Status:
Terminated
Trial end date:
2017-12-15
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well giving docetaxel and lapatinib ditosylate together as
second-line therapy works in treating patients with stage IV bladder cancer that cannot be
removed by surgery. Drugs used in chemotherapy, such as docetaxel, work in different ways to
stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the
enzymes needed for cell growth. Giving docetaxel and lapatinib ditosylate together may kill
more tumor cells.