Overview

Docetaxel in Breast Cancer

Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
Primary objective : - To compare disease-free survival after treatment with docetaxel in combination with doxorubicin and cyclophosphamide to doxorubicin and cyclophosphamide followed by docetaxel in operable adjuvant breast cancer HER2neu negative patients with positive axillary lymph nodes. Secondary objectives : - To compare toxicity and quality of life between the 2 above-mentioned arms. - To evaluate pathologic and molecular markers for predicting efficacy.
Phase:
Phase 3
Details
Lead Sponsor:
Sanofi
Collaborator:
Cancer International Research Group (CIRG)
Treatments:
Cyclophosphamide
Docetaxel
Doxorubicin
Liposomal doxorubicin