Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy?
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
In Norway, about 60% of all children with cerebral palsy (CP) are being treated with
botulinum toxin A (BoNT-A) at 6 years of age, mainly in the legs. Despite this widespread use
of the drug, the evidence for a positive effect on walking is insufficient. Moreover, large
variation in effect is seen by clinicians. The main objective of the present study is to
investigate whether injections with BoNT-A in the calf muscles make walking easier in
children with spastic CP within 6 months, reflected by reduced energy cost during walking.
Phase:
Phase 4
Details
Lead Sponsor:
St. Olavs Hospital
Collaborators:
Fondation Lenval Haukeland University Hospital Mazowieckie Centrum Neuropsychiatrii, Warszawa Norwegian University of Science and Technology Oslo University Hospital The Hospital of Vestfold University Hospital of North Norway
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA