Does Bowel Stimulation Before Loop Ileostomy Closure Reduce Postoperative Ileus?
Status:
Active, not recruiting
Trial end date:
2022-07-31
Target enrollment:
Participant gender:
Summary
Postoperative ileus is the most commonly observed morbidity following ileostomy closure.
Studies have previously demonstrated that the defunctionalized bowel of a loop ileostomy
undergoes a series of functional and structural changes. It has been hypothesized that these
changes may contribute to the development of postoperative ileus, and that stimulating the
distal limb of a loop ileostomy prior to closure may functionally prepare the excluded bowel
for intestinal transit.
The purpose of the multicenter, randomized controlled trial is to determine the impact of
preoperative stimulation of the distal limb of a loop ileostomy on postoperative ileus.
Phase:
N/A
Details
Lead Sponsor:
Jewish General Hospital
Collaborators:
Maisonneuve-Rosemont Hospital Montreal General Hospital North Shore Hospital, Waitemata District Health Board North York General Hospital Rush University Medical Center St. Mary's General Hospital St. Paul's Hospital, Canada Sunnybrook Health Sciences Centre