Does DHEA IVF Outcomes in Poor Responders?

• Status: Unknown status
• Trial end date: 2020-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

This study is a RCT to examine whether DHEA is capable of improving results for poor responders to ovarian stimulation during IVF treatment

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Homerton University Hospital NHS Foundation Trust
• Treatments: Dehydroepiandrosterone

Criteria

Inclusion Criteria:

• Age ≥ 40 years

• Markers for poor ovarian reserve (AMH <7 pmol/L(<1.1 ng/ml) and/or AFC< 7)

• Previous poor response to ovarian stimulation ( ≤3 oocytes with a conventional stimulation protocol)

Exclusion Criteria:

• Women > 42 years

• Women with premature ovarian failure / premature menopause (FSH>40 U/L). Women already taking DHEA.

• Patients with a known allergy to the trial drug or any of the active ingredients in the placebo.