Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
Clonidine is widely used off-label in children for several indications. Clonidine is used for
treatment and/or prevention of postoperative agitation in children anaesthetised with
Sevoflurane. The investigators don´t have solid evidence for the effect and the investigators
don´t have data for characterization of the pharmacokinetic profile among age-groups for
children 1-6 years.
In this study the investigators want to investigate if IV Clonidine administered at the end
of surgery can prevent/reduce postoperative agitation. Secondary outcomes include
measurements of postoperative pain relief and adverse effects, including a 30-day follow-up.