Does Intraoperative Methadone Prevent Postoperative Pain in Bariatric Surgery?

• Status: Completed
• Trial end date: 2017-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The recent increase in obesity has led to an increase in the need for bariatric surgery. In this group of patients the postoperative pain management is of vital importance. One strategy to improve postoperative analgesia is the use of intraoperative methadone, specially in those patients which regional anesthesia is not feasible. There is evidence that the use of intraoperative methadone can lead to a analgesia lasting 24 to 36 hours, while not associated with increased side effects when compared to other opioids with short or intermediate duration of action. In this study the investigators will evaluate the efficacy of intraoperative methadone in reducing postoperative pain and opioid consumption.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Treatments: Fentanyl; Methadone

Criteria

Inclusion Criteria:

• Open bariatric surgery

• No contraindications for any drugs used during the trial

• Read, understood and signed the informed consent

Exclusion Criteria:

• Laparoscopic bariatric surgery

• Known allergy to any drugs used during the trial

• Cardiovascular disease

• Creatinine clearance lower than 60 mL/min/1.73 m2

• Chronic usage of opioids

• History of personality disorder