Does Intravenous Lactated Ringer Solution Raise Measured Serum Lactate?

• Status: Completed
• Trial end date: 2017-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Lactated Ringer's (LR) solution bolus is commonly administered in the emergency department setting to seriously ill patients. It is also common to obtain blood samples to determine serum lactate levels to aid in the assessment of the patient's degree of illness. This study endeavors to determine if serum lactate levels are affected by LR fluid administration in healthy adult individuals as compared to those who receive Normal Saline (NS). Healthy adult volunteers will be used as subjects so that the illness of hospital patients does not confound the results.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Medical Center of Southern Nevada
• Treatments: Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Healthy adult volunteers

• 18 years and older

Exclusion Criteria:

• Pregnancy or currently breast-feeding

• Prisoner

• History of conditions associated with fluid overload: heart, renal or hepatic failure

• Baseline serum lactate level >2.2mmol

• Baseline creatinine > 1.5 mg/dL