Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?

• Status: Recruiting
• Trial end date: 2024-09-10
• Target enrollment: 0
• Participant gender: All

Summary

For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Texas Tech University Health Sciences Center, El Paso
• Treatments: Dexamethasone

Criteria

Inclusion Criteria:

• Meet ICHD-3 Migraine Headache Criteria

• Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2

• Nerve block performed with bupivacaine 0.5%

Exclusion Criteria:

• Head trauma

• Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma)

• Headache in the setting of viral syndrome

• Chronically on steroids

• Known allergy to dexamethasone

• Unable to reach the patient by phone or text for follow-up

• Gestational diabetes or other uncontrolled diabetes

• Known to be immunocompromised