Does Optimized General Anesthesia Care Reduce Postoperative Delirium?

• Status: Unknown status
• Trial end date: 2018-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in long-term care institutions. To date, the only intervention shown to be effective at minimizing postoperative delirium is a proactive geriatric consultation. This prospective randomized clinical trial will randomize 160 adults, aged 65 years or older, to either optimized general anesthesia or usual general anesthesia care for hip fracture surgery to determine if the optimized anesthesia management reduces the severity of postoperative delirium.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Missouri-Columbia
• Treatments: Anesthetics; Fentanyl; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• Subject or legal representative has voluntarily signed the informed consent approved by the Institutional Review Board,

• Hip fracture surgery scheduled under general anesthesia

• Subject is 65 years or older on the day of surgery

Exclusion Criteria:

• Inability to follow directions or comprehend the English language

• Severe uncorrected visual or auditory handicaps

• Delirium at screening or baseline

• Emergency surgery