Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?

• Status: Completed
• Trial end date: 2021-05-15
• Target enrollment: 0
• Participant gender: All

Summary

Investigators will assess if perineural dexamethasone can increase the duration of an ulnar nerve block when controlling for systemic effects in healthy volunteers.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Zealand University Hospital
• Treatments: BB 1101; Dexamethasone; Dexamethasone acetate; Lidocaine

Criteria

Inclusion Criteria:

• Age of 18 years or above

• Must fully understand the protocol and sign written informed consent

• American Society of Anaesthesiologists Physical Status Classification System of 1 or 2

• Body Mass Index above 18 kg/m^2

• For fertile women, safe contraceptives for the last month and negative urine human chorionic gonadotropin is required

Exclusion Criteria:

• Participants unable to cooperate

• Participants unable to speak or read Danish

• Age above 65 years

• Cardiovascular disease

• Allergy to study medication

• History of alcohol or substance abuse

• Intake of corticosteroids within the last 14 days

• Daily intake of prescription analgesia within the last four weeks

• Intake of over-the-counter analgesia within the last 48 hours

• Neuromuscular diseases or wounds on the arms or hands preventing adequate test or block performance.

• Diabetes mellitus