Does Perioperative Pregabalin Reduce Postoperative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery Under Spinal Anesthesia?

• Status: Completed
• Trial end date: 2019-02-08
• Target enrollment: 0
• Participant gender: All

Summary

The investigators hypothesize that perioperative oral administration of pregabalin would reduce postoperative pain and produce reduction in postoperative opioid consumption after anterior cruciate ligament (ACL) reconstruction . Patients are randomly assign to 1 of 2 groups. The placebo group receive placebo capsules 1 hour before surgery and 12 hours after initial dose. The pregabalin group receive pregabalin 150 mg, respectively at the same points.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• age between 20-65 years

• physical condition type I or II in ASA (American Society of Anesthesiology)

Exclusion Criteria:

• patients of ASA classification 3 or more

• with a history of cardiovascular or respiratory disease

• dizziness or frequent headache

• active alcohol or drug usage,

• intake of any analgesics daily or 48 hours before surgery

• impaired renal and/or hepatic function