Does Sevoflurane Cause Genomic Damage

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to find out if sevoflurane causes any cell damage to patients undergoing general anaesthesia. In case of any damage, the reversibility of the damage is also assessed. This is a prospective, comparative study carried out in all children scheduled for surgical repair of cleft lip or palate admitted in the Department of Plastic Surgery under Smile Train organisation ìn our hospital,who satisfy the inclusion and exclusion criteria.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jubilee Mission Medical College and Research Institute
• Treatments: Anesthetics; Propofol; Sevoflurane

Criteria

Inclusion Criteria

• Children must have isolated cleft lip or palate.

• The surgery must be a primary repair of cleft lip or palate.

• The minimum duration of the surgery must be 90 minutes.

Exclusion Criteria

• Children who have undergone previous surgery.

• Children who have syndromic cleft lip or palate.

• Children with bleeding disorders.

• Children with known allergy to any of the concerned drugs.