Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?

• Status: Active, not recruiting
• Trial end date: 2023-02-07
• Target enrollment: 0
• Participant gender: Female

Summary

This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of South Alabama
• Treatments: Clobetasol

Criteria

Inclusion Criteria:

• women with biopsy proven lichen sclerosus and significant symptoms based on Skindex-29 scores >21

Exclusion Criteria:

• prior vaginal mesh or pelvic radiation

• active genital infection

• Current or past gynecologic malignancy