Overview

Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection

Status:
Not yet recruiting

Trial end date:
2021-04-15

Target enrollment:
0

Participant gender:
All

Summary

Infection after spinal surgery is one of the serious complications. Spinal surgery infection can cause high morbidity, mortality, and costs. In spite of different prophylactic methods, up to 15% of infection appears after spinal surgery. Vancomycin powder, which is one of the most applied methods, seems to be effective and inexpensive. However, vancomycin administration may be inconvenient in elderly participants with high comorbidity and especially kidney problems. The investigators aimed to reduce the rate of infection in the post-op 90-day period by adding per-op Teicoplanin powder onto the implant in participants scheduled for lumbar posterior instrumentation.

Phase:

Phase 3

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Bezmialem Vakif University

Treatments:

Teicoplanin

Criteria

Inclusion Criteria:

- Lumbar spinal stenosis,

- LDH(Lumbar Disc Hernia)

- Lumbar degenerative scoliosis

- Lumbar spondylolisthesis

Exclusion Criteria:

- History of malignancy

- Systemic inflammatory disease

- Severe cardiac insufficiency

- Morbid obesity (>40 kg/m2 or 35 or more and experiencing obesity-related health
conditions)

- History of lumbar spine surgery