Does the Rapid Intravenous Administration of Oxytocin After Delivery of the Baby Decrease the Bleeding During Cesarean Section in Women at Risk of Bleeding During Cesarean Section?

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Oxytocin is normally given either rapidly into the vein (bolus) or put into an intravenous bag and administered more slowly, after delivery of the baby by cesarean section. Both of these methods are commonly used. To date there has been little research to demonstrate that one method of giving oxytocin is better than another in women who are more likely to bleed after delivery. The purpose of the study is to see whether a small bolus of oxytocin makes the uterus contract better to reduce bleeding and decreases the need to give additional oxytocin or more powerful drugs in women who are at risk for bleeding after delivery of their baby by cesarean section.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of British Columbia
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Aged 19 years or over

• Having a cesarean section

• Have one or more of the following

1. a larger than average uterus, because of

• a large baby

• twins, triplets, etc

• a large volume of fluid around the baby

2. have received oxytocin to help stimulate labor for eight or more hours before cesarean section

3. have infection inside the uterus that is treated with antibiotics

4. bleeding after giving prior birth

5. the placenta is in a position where it is more likely to bleed

6. have had five or more pregnancies before current one

Exclusion Criteria:

• Significant medical problem such that an oxytocin bolus might not be safe

• Active bleeding and their blood pressure or pulse rate are not normal

• Blood does not clot normally

• Aged less than 19 years

• Does not understand English