Domperidone for Gastroparesis in Solid Organ Transplantation

• Status: Terminated
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the clinical response to domperidone in solid organ transplant recipients with gastroparesis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: David J. Lederer, M.D.
• Treatments: Domperidone

Criteria

Inclusion Criteria:

• gastroparesis or gastroesophageal reflux that is refractory to standard therapy.

• signed informed consent

Exclusion Criteria:

• serious cardiac arrhythmias

• clinically significant bradycardia, sinus node dysfunction, or heart block.

• prolonged QTc

• clinically significant electrolyte disorders.

• gastrointestinal hemorrhage or obstruction.

• prolactinoma

• pregnant or breast feeding female

• known allergy to domperidone.