It is a randomized, double-blind, single-center, 30-day study. Patients aged 35-60 years,
with apnea and hypopnea index and respiratory disturbance index normalized with CPAP, and
Epworth Sleepiness Scale> 11. Patients undergo baseline and CPAP titration polysomnography,
liquor and blood collection, Multiple Sleep Latency Test, anxiety and depression and
cognitive assessments.