Overview

Donor Alloantigen Reactive Tregs (darTregs) for Calcineurin Inhibitor (CNI) Reduction

Status:
Completed
Trial end date:
2019-12-16
Target enrollment:
Participant gender:
Summary
This research study is for liver transplant recipients and their respective living donors. The purpose of this study is: 1. To see if it is safe for liver recipients to receive one dose of donor reactive T regulatory cells (Tregs) 2. To see if the Tregs allows a liver recipient to take less, or completely stop medications normally taken after receiving an organ transplant.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators:
Clinical Trials in Organ Transplantation in Children
Rho Federal Systems Division, Inc.
Treatments:
Acetaminophen
Calcineurin Inhibitors
Diphenhydramine
Promethazine