Dopamine Versus Norepinephrine Under General Anesthesia

• Status: Completed
• Trial end date: 2021-09-30
• Target enrollment: 0
• Participant gender: All

Summary

Participants under general anesthesia will be randomly treated with an adjusted dose dopamine or norepinephrine to elevate 10% of mean arterial pressure. Systemic hemodynamic data is recorded by PRAM and the change of cardiac index is compared between groups.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Hospital of Fudan University
• Treatments: Dopamine; Norepinephrine

Criteria

Inclusion Criteria:

• undertake cardiac surgery for congenital heart disease

Exclusion Criteria:

• Aortic valve or aortic disease

• severe arrhythmia

• use of cardiovascular active drugs before anesthesia

• need to use a combination of different cardiovascular support drugs after anesthesia