Overview
Dopamine and Muscle Function in the Heat
Status:
Active, not recruiting
Active, not recruiting
Trial end date:
2021-12-31
2021-12-31
Target enrollment:
0
0
Participant gender:
Male
Male
Summary
our goal is to study the effects of dopamine activity, using Ritalin ingestion, on neuromuscular function over the course of a progressive heating and cooling protocol developed in our lab. We hypothesize that Ritalin will minimize the previously reported progressive impairment in neuromuscular function with hyperthermia compared to placebo, suggesting that dopamine activity preserves neuromuscular capacity with hyperthermia.Phase:
N/AAccepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Brock UniversityTreatments:
Dopamine
Methylphenidate
Criteria
Inclusion Criteria:- High aerobic fitness (>55 mL/kg/min maximal aerobic capacity)
Exclusion Criteria:
- diagnosed cardiovascular, respiratory and/or neuromuscular disease, prescription of
Ritalin or any drugs for hyperactivity within the past 1 year, any current
prescription medication (except for asthma/allergy inhalers), any contraindications to
Ritalin.