Overview

Dopamine and Norepinephrine Infusion With Restricted Hydration

Status:
Completed

Trial end date:
2018-12-15

Target enrollment:
0

Participant gender:
All

Summary

This study was designed to assess the effect of adding dopamine infusion in addition to restrictive hydration combined with noradrenaline infusion on intraoperative serum lactate levels as an indicator for tissue hypo perfusion and renal function in comparison to restrictive hydration combined with noradrenaline infusion only and standard hydration during open abdominal surgeries.

Phase:

N/A

Accepts Healthy Volunteers?

Accepts Healthy Volunteers

Details

Lead Sponsor:

Ain Shams University

Treatments:

Dopamine
Norepinephrine

Criteria

Inclusion Criteria:

- All patients with American Society of Anesthesiologists (ASA) physical status I or II

- Age range from 18-80 years scheduled to either radical cystectomy or hemicolectomy
were contained in the study.

Exclusion Criteria:

- Patients with coagulopathies,

- Hepatic dysfunction (prothrombin ratio <50%),

- Renal dysfunction,

- Congestive heart failure (New York Heart Association scores ≥3),

- Contraindications for epidural analgesia (e.g. patient refusal, local infection or
coagulopathy), and peripheral vascular disease.