Overview

Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)

Status:
Completed
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
Dr. Kevin J. Black at Washington University is conducting a study to learn whether we can use MRI scans to test dopamine function in the brain and to determine whether the brain performs memory tasks differently in Tourette Syndrome (TS). TS is a movement disorder characterized by vocal tics (sounds) and motor tics (movements). We will measure how and where brain activity changes using magnetic resonance imaging (MRI) scans during memory tasks and after taking levodopa. Levodopa is a drug commonly used for the treatment of Parkinson's disease (PD), a very different movement disorder.
Phase:
Phase 1
Details
Lead Sponsor:
Kevin J. Black, MD
Washington University School of Medicine
Collaborator:
National Institute of Mental Health (NIMH)
Treatments:
Dihydroxyphenylalanine
Dopamine
Dopamine Agents
Dopamine Agonists
Levodopa
Pharmaceutical Solutions