Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dyslexia

• Status: Unknown status
• Trial end date: 2015-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

This study aims to determine whether levodopa, in combination with a high frequency training of (grammatical) rules, is effective in boosting learning success in healthy subjects and whether this kind of training in combination with levodopa improves reading and spelling abilities of patients with dyslexia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital Muenster
• Treatments: Dopamine; Dopamine Agents; Dopamine Agonists; Levodopa

Criteria

Inclusion Criteria:

• Right-handedness

• Age between 18-35 years

• Primary language: German

Exclusion Criteria:

• Known allergy to levodopa or tetrazine

• History of medication/drug abuse

• Acute nicotine withdrawal or > 10 cigarettes per day

• >6 cups/glasses of coffee, caffeine drinks or energy drinks per day

• >50 grams of alcohol per day

• Hypertonia

• Arteriosclerosis

• Diabetes, asthma, or glaucoma

• Psychiatric disease

• Neurologic disease

• Other medication