Dosage Effects of Folic Acid on Blood Folates of Honduran Women

• Status: Completed
• Trial end date: 2005-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

CDC staff at the National Center on Birth Defects and Developmental Disabilities have been working closely with a Honduras-based organization, Project Healthy Children (PNS) and the Ministry of Health, on a folic acid supplementation study among female maquila workers. Participants are divided into two groups. One group receives a 1.0 milligram pill daily while the other group receives a 5.0 milligram pill weekly. The aim of this study is to assess serum blood folate levels measured at baseline, midpoint, and endpoint of the study. Hypothesis: Folic acid (5mg)given once weekly is as effective as folic acid (1mg)given daily in raising blood folate levels.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Centers for Disease Control and Prevention
• Collaborators: Ministry of Health, Honduras; Project Healthy Children
• Treatments: Folic Acid; Vitamin B Complex

Criteria

Inclusion Criteria:

minimum employment in factory 6 mths

-

Exclusion Criteria:

• pregnant

• currently consuming folic acid

• prior birth-defect affected pregnancy

• chronic disease

• currently taking folic acid antagonist