Overview Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders Status: Completed Trial end date: 2008-12-01 Target enrollment: Participant gender: Summary The purpose of this study is to determine whether HPN-100 is safe and tolerable in subjects with Urea Cycle Disorders. Phase: Phase 2 Details Lead Sponsor: Horizon Pharma Ireland, Ltd., Dublin IrelandTreatments: 4-phenylbutyric acidGlycerol