Dose Escalation of Different Concentrations of ZK 245186 in Atopic Dermatitis

• Status: Completed
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the safety and efficacy of three concentrations of ZK 245186 ointment and vehicle on increasing body surface areas for the treatment of atopic dermatitis and to obtain dose-response information for the three concentrations.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bayer

Criteria

Inclusion Criteria:

• diagnosis of atopic dermatitis (Hanifin and Rajka criteria)

• mild to moderate atopic dermatitis at beginning of study

• wash-out periods for systemic and topical treatments for atopic dermatitis

• females must use effective contraception

Exclusion Criteria:

• pregnant or lactating women

• conditions that in the opinion of the investigator may pose a risk or interfere with the evaluation of the study

• wide-spread atopic dermatitis requiring systemic treatment

• diagnosed with immunocompromised status

• skin diseases - other than atopic dermatitis - in the treatment area

• mental handicap or legally incompetent