Dose Response Effects of Inhaled Fluticasone on Airway Effects of Hypertonic-saline in Asthma

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study investigates the effect of a inhaled corticosteroid (fluticasone or "Flovent") on airway narrowing induced by hypertonic saline (salty water). The study hypothesis is that fluticasone will be more effective in preventing saline-induced airway narrowing than methacholine-induced narrowing.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of California, San Francisco
• Collaborators: GlaxoSmithKline; National Heart, Lung, and Blood Institute (NHLBI)
• Treatments: Fluticasone

Criteria

Inclusion Criteria:

• Clinical diagnosis of asthma

Exclusion Criteria:

• Habitual cigarette smoking